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Pharmacel® sMCC 90

Multi- and highly- functional excipient

Superior compaction and flow properties

Ensures formulation robustness and easy scale-up

Produktinformation

Pharmacel^® sMCC 90, a silicified microcrystalline cellulose, developed as the synergistic solution for challenging oral solid dosage formulations. Co-processing microcrystalline cellulose with silicon dioxide increases its surface area, resulting in enhanced powder flow, superior tabletability, and improved formulation robustness.

Pharmacel® sMCC 90 benefits

This new addition to our well-established excipients’ portfolio offers customers worldwide the highest quality excipients and services. Pharmacel® sMCC 90 has the following benefits compared to conventional excipients:

- Improved tablet compression

- Higher production speeds

- Rapid formulation development

Improved tablet compression

Pharmacel® sMCC 90 is a highly functional excipient for direct compression processes. In comparison with conventional excipients, Pharmacel® sMCC 90 leads to lower capping of tablets at high compaction speed thereby enabling 20% harder tablets.

Higher production speeds

The production speed of tablets depends on the pace of several intermittent steps. Pharmacel® sMCC 90 enables higher processing speed in n multiple units of operation. Additionally, Pharmacel® sMCC 90 allows for a swift and more consistent flow from the hopper.

Die Fließfähigkeit von Pharmacel® sMCC 90 ermöglicht ein gleichmäßiges Tablettengewicht mit Gewichtsschwankungen von weniger als 1 % bei 250 mg-Placebotabletten.

Schnelle Formulierungsentwicklung

Pharmacel® sMCC 90 entschärft die Herausforderungen bei der Formulierung aufgrund seiner im Vergleich zu herkömmlichen Hilfsstoffen verbesserten Fließfähigkeit und Verdichtung. Darüber hinaus ermöglicht die geringe Empfindlichkeit gegenüber Schmiermitteln und Verweilzeiten ein einfaches Scale-up. Darüber hinaus reduziert Pharmacel® sMCC 90 die Anzahl der Hilfsstoffe im Vergleich zu herkömmlichen Sorten und macht die Verarbeitung von Kieselsäure überflüssig.

Verpackung

- 25 kg Mehrschichtiger Papiersack mit PE-Folie

- Probengröße: 500g

Produktionsstandort

Nagpur, Indien

Haltbarkeit

36 Monate Wiederholungsprüfung

Documentation

ALBA Pharmacel
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Oral Solid Dose Brochure Ansehen
Kontaminanten-Erklärung Pharmacel
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Lebensmittelerklärung MCC
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GMO-Erklärung Mikrokristalline Cellulose
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GMP DFE Pharma Indien Nagpur
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ISO 14001 DFE Pharma Indien Cuddalore
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ISO 9001 DFE Indien Cuddalore
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ICHQ3D - Elementare Verunreinigungen MCC
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Inhaltsstoffdeklaration Laktose
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Inhaltsstoffdeklaration Pharmacel
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Koscher-Zertifikat DFE Pharma Indien Cuddalore
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Sicherheitsdatenblatt Pharmacel
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Nährwertangaben Pharmacel
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Inhaltsstoffdeklaration Pharmacel sMCC
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Sicherheitsdatenblatt Pharmacel sMCC
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DMF (Drug Master File)
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Produktspezifikation sMCC
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sMCC90 Brochure Ansehen

cGMP-Erklärung
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BSE-Erklärung Laktose & Inhalation
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Bestrahlungsfrei
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Verunreinigungen und Rückstände Laktose
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Inhaltsstoffdeklaration Pharmacel sMCC
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Abwesenheit von Melamin Pharmacel, SuperStarch, Zerfallsmitteln
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Welt-Anti-Doping-Code
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Ungefährlicher Stoff
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BSE-Erklärung Pharmacel®
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Restliches Lösungsmittel Pharmacel
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Haltbarkeitsangabe Pharmacel
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Haltbarkeitserklärung Pharmacel sMCC
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Re-compaction properties of lactose and mcc Ansehen
Roller compaction of anhydrous lactose and mcc Ansehen
MCC Effect of Increasing Pharmacel Concentration on the Tableting Properties of DC Diluents Ansehen
Impact of excipient and blend properties on feeding consistency for continuous manufacturing Ansehen
Choosing the optimal lactose and MCC grade for formulating moisture sensitive drugs Ansehen

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